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Novel Methods for the Visualization and Analysis of Functional Maps in Cortex

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Flat Maps 31 The  curvature  can  then  be  color-coded,  e.g.,  different  gray  values  can  be  used  for different ranges of curvature. mrFindBorders only uses functional flat maps; it does not use anatomical flat maps. When showing a visual stimulus, instead of measuring the amplitude of the responses in visual areas, phase data and coherence data of the responses can be derived from the fMRI data.  Different  functional  flat  maps  are  known.  Here,  only  the  functional  flat  maps  that mrFindBorders uses are explained. Especially phase data is important because the pattern in phase data can be used to separate visual areas. 3.8.1 Phase Maps As explained before, the areas V1, V2, and V3 are retinotopically organized. Because of this, it is possible to control the location of the neural activity by choosing appropriate visual stim- uli [Wandell, 1999 #16]. When presenting a subject with a flickering contracting (Figure 13 A) or expanding (Figure 14 A) ring visual stimulus, the signal at each location within the vis- ual field changes periodically. The contrast reversal rate (flicker frequency) is, for example, 8Hz. The contrast reversal is used to improve the response during the activation periods. The stimulus alternation frequency is, for example, 1/36 Hz. When measuring the neural responses at different locations in a retinotopic visual area, a flickering expanding ring visual stimulus with a constant velocity (from the fovea to the periphery) causes all signals (from the different locations in the visual cortex) to vary at the same frequency. However, the temporal phase of the signals varies depending on the location in cortex in eccentricity direction (see section 3.4 about fMRI). The phase values can be color-coded (Figure 14 D). The color ring shows the mapping between eccentricity and colors. The stimulus shown in Figure 14 A creates a travel- ing wave (Figure 14 C) [Wandell, 1999 #16]. Therefore, to create a wave of neural activity that travels across cortex in the eccentricity dimension, a contracting or expanding flickering ring visual stimulus (Figure 13 A) can be used. The neural activity can be measured in differ- ent visual areas, including V1, V2, and V3.
  
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