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Novel Methods for the Visualization and Analysis of Functional Maps in Cortex

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ISBN: 3540293744   ISBN: 3540293744   ISBN: 3540293744   ISBN: 3540293744 
 
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Anatomy and Physiology 9 The cortex can be separated into two hemispheres [Teo, et al., 1997 #8]. Area V1 in the left hemisphere only receives information from the right visual field and vice versa. As explained before, the cortex in general is a layered structure. For example, area V1 can be subdivided into  6  layers,  it  is  about  3-4  mm  thick  (Brian  A.  Wandell,  personal  communication,  June 2001), and the area is about 4 cm by 8 cm large [Wandell, 1999 #16]. Different layers have different relative densities of neurons, axons, and synapses. They also interconnect to different parts of the brain. The underlying white matter consists of axons that carry the signals from and to the different cortex regions.   Area V1 can be anatomically identified because of a dense collection of myelinated ax- ons, which causes a striation. Beyond V1, the visual cortex can be divided into many more different visual areas [Schmidt, 1999 #17]. Different visual areas are specialized to respond to different pattern of activity, e.g., shape, or moving pattern [Müschen, 2000 #18]. The visual areas are an important part of cortex organization. Researches try to find out what purposes they have. Figure 2 (bottom) shows the visual areas V1, V2, V3, V3a, and V4.   The  components  of  the  visual  pathway  are retinotopically arranged, i.e., “they preserve the map of the visual field that falls on the retina” [Khan, 1999 #19]. For example, the topol- ogy of the receptive fields in the LGN is similar to the organization in the retina. The same is true for area V1. Area V1 is retinotopically organized. The full visual field can be mapped retinotopically in V1. Adjacent points in the visual field map onto adjacent points in the reti- notopically organized visual cortex [Hurdal and McElwain, 1995 #20]. Not only the primary visual cortex (V1) shows this retinotopic organization. Nearby areas, such as V2 and V3, are also retinotopically organized.   Area V1 of each hemisphere represents an entire hemifield (half of the visual field). The same is true for V2 and V3, but it can be seen that the areas V2 and V3 are each split into two parts: one on the dorsal1 side (V2d, V3d), and the other one on the ventral1 (V2v, V3v) side. V2d and V3d each represent the lower part of the visual field; V2v and V3v each represent the upper part of the visual field.                                                   1 Please refer to the glossary.
  
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